Latest News

Counting CTCs in blood predicts prostate cancer treatment response

A drop in the number of cancer cells detected in a patient’s blood could be the best indicator yet as to whether treatment for prostate cancer is working. A new study, published in European Urology, ....

Featured White Paper

Quality Systems for Multiplex Immunoassay Testing Services for Clinical Trials

This Quality Control White Paper highlights the measures implemented by Myriad RBM that take Luminex xMAP technology to a high level of reproducibility and ruggedness. The Myriad RBM platform combines the sensitivity and dynamic range of microsphere-based immuno-multiplexing with the precision and dependability of automated liquid handling. Together these features set Myriad RBM apart from other biomarker testing labs by offering the highest quality and cost-effective immunoassay measurements.

Biomarkers

Targeted next generation sequencing identifies markers of response to PD-1 blockade.

Therapeutic antibodies blocking programmed death-1 and its ligand (PD-1/PD-L1) induce durable responses in a substantial fraction of melanoma patients. We sought to determine whether the number and/or ....

Decision Algorithms

Lyme disease: the promise of Big Data, companion diagnostics and precision medicine.

Lyme disease caused by the spirochete Borrelia burgdorferi has become a major worldwide epidemic. Recent studies based on Big Data registries show that >300,000 people are diagnosed with Lyme disease ....

Product News

Agilent collaboration to develop cancer diagnostics in China

SANTA CLARA. Agilent Technologies Inc. and Burning Rock today announced they have signed an agreement under which Burning Rock will develop cancer diagnostics in China based on the Agilent SureSelect ....

Imaging

How Patients View Lung Cancer Screening: The Role of Uncertainty in Medical Decision Making.

Radiographic lung cancer screening guidelines and coverage requirements warrant a shared decision making process. Guidance is needed regarding how to conduct shared decision making effectively. A usef ....

Omics

CRISPR-Cas9 therapeutics in cancer: promising strategies and present challenges.

Cancer is characterized by multiple genetic and epigenetic alterations that drive malignant cell proliferation and confer chemoresistance. The ability to correct or ablate such mutations holds immense ....

Pipeline News

Combining Cytokine-based Immunotherapy AM0010 with Pembrolizumab yielded durable responses in patients with advanced solid tumors

​​NEW YORK. A combination of the immunotherapies AM0010 and the immune checkpoint inhibitor pembrolizumab was well tolerated and resulted in durable objective tumor responses in some patients with ....

Issued Patents

Blood Markers For Diagnosing Epithelium Derived Cancers And Monoclonal Antibodies Thereof

The present invention provides uses of cytokeratins as markers for diagnosing epithelium derived cancers. The present invention provides cancer-related epitopes of cytokeratins and monoclonal antibodi ....

Patent Applications

Dna-decorated Graphene Chemical Sensors

The present invention provides a broad response single-stranded DNA-graphene chemical sensor device. The present invention also provides methods for improving the ability of graphene to work as a chem ....

Bioinformatics

A Bayesian integrative approach for multi-platform genomic data: A kidney cancer case study.

Integration of genomic data from multiple platforms has the capability to increase precision, accuracy, and statistical power in the identification of prognostic biomarkers. A fundamental problem face ....

Funding News

Color Genomics raises $45 million in Series B financing

BURLINGAME. Color Genomics announced a $45 million investment led by General Catalyst with participation from Bono, singer-songwriter and philanthropist, and existing investors including Susan L. Wagn ....

Sensors and Wearables

Nanoscale electronic motion sensor as DNA sequencer

GAITHERSBURG. Researchers from the National Institute of Standards and Technology (NIST) and collaborators have proposed a design for the first DNA sequencer based on an electronic nanosensor that can ....

Recruiting Trials

Inflammatory Response in Myocardial Infarction Evaluated by MRI and Biomarkers

An intense inflammatory reaction is triggered by the ischemic injury during myocardial infarction. The inflammatory processes involved are complex and haven’t been explored in detail in hu ....